Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321191 | 0.91 | MAPT (0.37) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL7306628 | 0.89 | TSHR (0.46) | MAPTGAAALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL7320975 | 0.88 | TSHR (0.45) | MAPTGAAALDH1A1HTTKDM4E | |
| SCHEMBL7310775 | 0.86 | L3MBTL1 (0.39) | MAPTALDH1A1HTTMEN1MAPK1 | |
| SCHEMBL7311708 | 0.82 | RAB9A (0.37) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL7310516 | 0.81 | RAB9A (0.37) | MAPTGAAALDH1A1HTTMEN1 | |
| SCHEMBL7312409 | 0.80 | TSHR (0.46) | MAPTGAAALDH1A1HTTKDM4E | |
| SCHEMBL7307845 | 0.80 | MAPT (0.37) | MAPTGAAALDH1A1HTTMEN1 | |
| Hydrochloric Acid SCHEMBL7321199 | 0.79 | TSHR (0.45) | MAPTGAAALDH1A1HTTKDM4E | |
| SCHEMBL7318533 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1HTTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |