Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321773 | 0.85 | PDK2 (0.51) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL7324040 | 0.84 | PDK2 (0.51) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL18386005 | 0.79 | THRB (0.45) | PDK2LMNAMAPTSMN1; SMN2P2RX1 | |
| SCHEMBL813078 | 0.79 | THRB (0.52) | PDK2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL30345614 | 0.79 | THRB (0.52) | PDK2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL7314066 | 0.79 | PDK2 (0.57) | PDK2ALDH1A1LMNAL3MBTL1P2RX1 | |
| SCHEMBL7322740 | 0.79 | PDK2 (0.53) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL17816933 | 0.77 | THRB (0.50) | PDK2ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL22797340 | 0.76 | PDK2 (0.50) | PDK2 | |
| SCHEMBL23655327 | 0.76 | PDK2 (0.61) | PDK2NPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |