Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | CLPP | Q16740 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3641713 | 0.85 | CAPN1 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL3642692 | 0.85 | CAPN1 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL3642696 | 0.85 | CAPN1 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL7323993 | 0.84 | CHRNB2 (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL24009922 | 0.80 | CTRB1 (0.55) | PYGLHPGDS | |
| SCHEMBL7322673 | 0.80 | CAPN1 (0.73) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL6942085 | 0.80 | CAPN1 (0.73) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL3644518 | 0.78 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL3641714 | 0.78 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL3642697 | 0.78 | CHRNB2 (0.55) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |