Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CLPP | Q16740 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322290 | 0.84 | CHRNB2 (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4CAPN1 | |
| SCHEMBL29615051 | 0.83 | EPHX2 (0.51) | MMP8LMNAPYGL | |
| SCHEMBL14120685 | 0.82 | PYGL (0.39) | PYGLROCK2ROCK1BACE1TP53 | |
| SCHEMBL14120684 | 0.82 | PYGL (0.39) | PYGLROCK2ROCK1BACE1TP53 | |
| SCHEMBL14121467 | 0.81 | MME (0.39) | CAPN1MMP8PYGLBACE1HPRT1 | |
| SCHEMBL14121466 | 0.81 | MME (0.39) | CAPN1MMP8PYGLBACE1HPRT1 | |
| SCHEMBL14120935 | 0.81 | CTSA (0.39) | PYGLROCK2ROCK1BACE1TP53 | |
| SCHEMBL14120934 | 0.81 | CTSA (0.39) | PYGLROCK2ROCK1BACE1TP53 | |
| SCHEMBL14120772 | 0.80 | PYGL (0.38) | CAPN1MMP8LMNAPYGLBACE1 | |
| SCHEMBL14120774 | 0.80 | PYGL (0.38) | CAPN1MMP8LMNAPYGLBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |