SCHEMBL7322330

SCHEMBL7322330

c1cc(N2CCC(N3CCNCC3)CC2)ccc1C1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 10/20 0.56
L3MBTL1 Q9Y468 10/20 0.56
HPGD P15428 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MBTD1 Q05BQ5 3/20 0.47
SLC18A3 Q16572 1/20 0.46
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
KHK P50053 3/20 0.43
TP53BP1 Q12888 2/20 0.43
L3MBTL4 Q8NA19 1/20 0.43
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6618068 0.88 ADRB1 (0.52) HPGDKMT2ASMN1; SMN2THRB
Bromide SCHEMBL6539610 0.86 ADRB1 (0.50) HPGDKMT2ASMN1; SMN2THRB
SCHEMBL38661103 0.82 ADRB1 (0.53) HPGDKMT2ASMN1; SMN2
SCHEMBL7315490 0.81 L3MBTL3 (0.50) L3MBTL3L3MBTL1KMT2AMBTD1SLC18A3
SCHEMBL4252026 0.79 ADRB1 (0.57) HPGDKMT2ASMN1; SMN2
SCHEMBL23339691 0.78 L3MBTL3 (0.58) L3MBTL3L3MBTL1HPGDKMT2ASMN1; SMN2
SCHEMBL18311444 0.78 ADRB1 (0.68) L3MBTL3L3MBTL1HPGDKMT2ASMN1; SMN2
SCHEMBL22174801 0.78 L3MBTL1 (0.58) L3MBTL3L3MBTL1HPGDKMT2ASMN1; SMN2
SCHEMBL27745904 0.78 L3MBTL3 (0.71) L3MBTL3L3MBTL1HPGDKMT2ASMN1; SMN2
SCHEMBL7324507 0.77 L3MBTL3 (0.53) L3MBTL3L3MBTL1KMT2AMBTD1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1240713-C New compound FUJISAWA PHARMACEUTICAL CO (JP) 2006-02-08 CN disclosed
CN-1296494-A New compound FUJISAWA PHARMACEUTICAL CO (JP) 2001-05-23 CN disclosed
US-6232290-B1 FUNGICIDES AGAINST PNEUMOCYSTIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-15 US disclosed
EP-1053247-A1 ANTIFUNGAL CYCLOHEXAPEPTIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-22 EP disclosed
WO-1999040108-A1 NEW COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-08-12 WO disclosed