Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332769 | 0.94 | F10 (0.48) | F10PTGESF2PRSS1PRSS2 | |
| SCHEMBL7321924 | 0.87 | SLC6A3 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| Bicarbonate SCHEMBL7333292 | 0.86 | SLC6A3 (0.46) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7331841 | 0.85 | ESR1 (0.50) | PARP10ALDH1A1SMN1; SMN2GAAMAPT | |
| Bromide SCHEMBL7330269 | 0.84 | ESR1 (0.49) | PARP10ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL10851091 | 0.81 | FTO (0.52) | F10F2PRSS1ST14PARP10 | |
| SCHEMBL7324828 | 0.81 | FTO (0.47) | F10F2PRSS1PARP10ALDH1A1 | |
| Methane SCHEMBL11282601 | 0.80 | F2 (0.58) | F10F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL10925845 | 0.79 | F2 (0.51) | F2MRGPRX1 | |
| Acetic Acid SCHEMBL10926648 | 0.79 | ATM (0.51) | F10F2MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |