Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641474 | 0.94 | OPRM1 (0.36) | RENCCR1 | |
| SCHEMBL7385303 | 0.90 | REN (0.47) | REN | |
| SCHEMBL7326621 | 0.89 | REN (0.42) | REN | |
| SCHEMBL7319576 | 0.89 | REN (0.40) | REN | |
| Hydrochloric Acid SCHEMBL7323642 | 0.88 | REN (0.42) | REN | |
| Hydrochloric Acid SCHEMBL7354434 | 0.88 | REN (0.39) | REN | |
| SCHEMBL7323158 | 0.87 | REN (0.43) | REN | |
| SCHEMBL7309930 | 0.86 | REN (0.46) | REN | |
| Hydrochloric Acid SCHEMBL7314911 | 0.86 | REN (0.43) | REN | |
| SCHEMBL7314665 | 0.86 | REN (0.46) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231919-B1 | N-HETEROCYCLIC ALCOHOL RENIN INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1993-01-20 | — | — | EP | disclosed |
| EP-0231919-A2 | N-Heterocyclic alcohol renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-08-12 | — | — | EP | disclosed |