Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322473 | 0.90 | REN (0.37) | REN | |
| SCHEMBL7316049 | 0.89 | REN (0.42) | RENCTSS | |
| SCHEMBL9641474 | 0.86 | OPRM1 (0.36) | REN | |
| SCHEMBL7323158 | 0.83 | REN (0.43) | REN | |
| Hydrochloric Acid SCHEMBL7314911 | 0.83 | REN (0.43) | REN | |
| SCHEMBL7403552 | 0.82 | REN (0.44) | REN | |
| SCHEMBL7326621 | 0.81 | REN (0.42) | REN | |
| SCHEMBL7385301 | 0.81 | REN (0.66) | REN | |
| Hydrochloric Acid SCHEMBL7323642 | 0.81 | REN (0.42) | REN | |
| SCHEMBL7319576 | 0.80 | REN (0.40) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055466-A | Renin inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1991-10-08 | — | — | US | claimed |
| US-5055466-A | Renin inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1991-10-08 | — | — | US | disclosed |