Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473812 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ACECYP2C19SMN1; SMN2 | |
| SCHEMBL3643939 | 0.83 | ALDH1A1 (0.48) | ALDH1A1ACECYP2C19SMN1; SMN2 | |
| SCHEMBL7644709 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ACECYP2C19SMN1; SMN2 | |
| SCHEMBL10979291 | 0.81 | FKBP1A (0.37) | KMT2AFKBP1AALDH1A1SLC6A2SLC6A3 | |
| Acetamide SCHEMBL1358326 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ACESMN1; SMN2 | |
| Acetamide SCHEMBL1358328 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ACESMN1; SMN2 | |
| SCHEMBL7644711 | 0.79 | MMP2 (0.39) | MMP2ALDH1A1ACEMAPTSMN1; SMN2 | |
| SCHEMBL8718972 | 0.78 | AR (0.41) | KMT2AALDH1A1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL20291082 | 0.76 | BRD4 (0.51) | — | |
| SCHEMBL14590316 | 0.75 | MMP2 (0.48) | LTA4HKMT2AMMP2ANPEPSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115091-A1 | N-carboxyacyl derivatives of cyclic amino acids, useful as antihypertensives | ENI-Ente Nazionale Idrocarburi (IT) | 1984-08-08 | — | — | EP | disclosed |