Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322563 | 1.00 | HRH4 (0.50) | HRH4MMEACEMMEL1ECE1 | |
| Hydrochloric Acid SCHEMBL7307585 | 0.90 | HRH4 (0.48) | HRH4MMEACEMMEL1ECE1 | |
| SCHEMBL7348558 | 0.90 | MME (0.48) | MMEACEMMEL1ECE1L3MBTL1 | |
| SCHEMBL7312321 | 0.90 | MME (0.48) | MMEACEMMEL1ECE1L3MBTL1 | |
| SCHEMBL489232 | 0.86 | MMEL1 (0.64) | MMEACEMMEL1ECE1 | |
| SCHEMBL489231 | 0.86 | MMEL1 (0.64) | MMEACEMMEL1ECE1 | |
| Bromide SCHEMBL9683926 | 0.85 | MMEL1 (0.62) | MMEACEMMEL1ECE1 | |
| SCHEMBL7316905 | 0.84 | L3MBTL1 (0.45) | MMEACEMMEL1ECE1L3MBTL1 | |
| Bromide SCHEMBL7311466 | 0.84 | MME (0.45) | MMEACEMMEL1ECE1 | |
| SCHEMBL7383477 | 0.83 | MME (0.54) | HRH4MMEACEMMEL1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |