Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993240 | 0.78 | EPHX1 (0.31) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL13640056 | 0.78 | EPHX1 (0.31) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL13640033 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11741166 | 0.72 | — | — | |
| SCHEMBL23777181 | 0.71 | — | — | |
| SCHEMBL27284402 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL27669782 | 0.67 | TP53 (0.30) | MEN1ALDH1A1LMNAALOX12KMT2A | |
| SCHEMBL15151738 | 0.66 | EPHX1 (0.35) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL8502985 | 0.66 | LMNA (0.38) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL9897847 | 0.66 | LMNA (0.38) | EPHX1SSTR4PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389898-A2 | Peptide derivatives of amino acids having a renin-inhibiting effect | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-03 | — | — | EP | disclosed |