Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640056 | 1.00 | EPHX1 (0.31) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL13640033 | 0.97 | ALDH1A1 (0.32) | ALDH1A1CYP2C19 | |
| SCHEMBL27284402 | 0.92 | ALDH1A1 (0.32) | ALDH1A1CYP2C19 | |
| SCHEMBL26854549 | 0.87 | — | — | |
| SCHEMBL459028 | 0.87 | — | — | |
| SCHEMBL11741166 | 0.79 | — | — | |
| SCHEMBL23777181 | 0.78 | — | — | |
| SCHEMBL7322787 | 0.78 | EPHX1 (0.32) | EPHX1SSTR4PDK1PDK2PDK3 | |
| SCHEMBL916056 | 0.76 | — | — | |
| SCHEMBL29046914 | 0.76 | TRPA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961946-B2 | Hair processing agent and method for permanent waving hair | SHOWA DENKO K.K. (JP) | 2015-02-24 | — | — | US | disclosed |
| CN-101669887-B | Hair processing agent and method for permanent waving hair | SHOWA DENKO KK | 2012-12-05 | — | — | CN | disclosed |
| US-8309730-B2 | Nonsteroidal compounds useful as modulators of glucocorticoid receptor AP-1 and/or NF-kappab acitivity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-20110263494-A1 | NONSTEROIDAL COMPOUNDS USEFUL AS MODULATORS OF GLUCOCORTICOID RECEPTOR AP-1 AND/OR NF-KAPPAB ACITIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2011-10-27 | — | — | US | disclosed |
| CN-101083975-B | Hair treatment agent and hair waving method | SHOWA DENKO KK | 2010-12-01 | — | — | CN | disclosed |
| CN-101669887-A | Hair processing agent and method for permanent waving hair | SHOWA DENKO KK | 2010-03-17 | — | — | CN | disclosed |
| US-20080085251-A1 | even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; | RESONAC CORPORATION (JP) | 2008-04-10 | — | — | US | disclosed |
| CN-101083975-A | Hair treatment agent and hair waving method | SHOWA DENKO KK (JP) | 2007-12-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263494-A1 | NONSTEROIDAL COMPOUNDS USEFUL AS MODULATORS OF GLUCOCORTICOID RECEPTOR AP-1 AND/OR NF-KAPPAB ACITIVITY AND USE THEREOF | NFKBIA, RELA, NR3C1 | EPHX1 1838/4885SSTR4 2555/4885PDK1 937/4885 |
| US-20080085251-A1 | even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; | TST, CYSLTR1, CYSLTR2 | EPHX1 1612/4885SSTR4 3448/4885PDK1 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.