Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918673 | 0.95 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL457893 | 0.90 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL18517409 | 0.86 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL19971674 | 0.86 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL8922062 | 0.86 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL14801745 | 0.83 | USP30 (0.53) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL14801743 | 0.83 | USP30 (0.53) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL9052122 | 0.83 | USP30 (0.53) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL14037432 | 0.83 | USP30 (0.62) | ALDH1A1L3MBTL1ATMCCR8KDM4E | |
| SCHEMBL1872029 | 0.83 | L3MBTL1 (0.65) | ALDH1A1L3MBTL1ATMCCR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181205-B | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2022053046-A1 | PYRAZOLOPYRIDINE COMPOUND OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
| CN-114181205-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |
| WO-1992012149-A1 | AZABICYDIC AND AZATRICYDIC DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM PLC (GB) | 1992-07-23 | — | — | WO | disclosed |