Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322807 | 0.95 | ALDH1A1 (0.56) | L3MBTL1ATMALDH1A1KDM4EHSD17B10 | |
| SCHEMBL457893 | 0.87 | ALDH1A1 (0.51) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL18517409 | 0.84 | ALDH1A1 (0.55) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL19971674 | 0.84 | ALDH1A1 (0.55) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL8922062 | 0.84 | ALDH1A1 (0.55) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL14037432 | 0.81 | USP30 (0.62) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL13177349 | 0.81 | USP30 (0.62) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL853540 | 0.81 | USP30 (0.62) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL1055082 | 0.81 | USP30 (0.62) | L3MBTL1ATMALDH1A1KDM4ECCR8 | |
| SCHEMBL1872029 | 0.81 | L3MBTL1 (0.65) | L3MBTL1ATMALDH1A1KDM4ECCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| US-5422354-A | Quinuclidine derivatives | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| WO-1992001688-A1 | QUINUCLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-02-06 | — | — | WO | disclosed |