Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697170 | 0.95 | MEN1 (0.56) | MEN1KMT2AAKR1C3CYP19A1MAPT | |
| SCHEMBL8366277 | 0.86 | MEN1 (0.49) | MEN1KMT2AAKR1C3MAPTHTT | |
| SCHEMBL7316591 | 0.85 | AKR1C3 (0.58) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7323404 | 0.85 | AKR1C3 (0.58) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8367782 | 0.84 | SMN1; SMN2 (0.75) | MEN1KMT2AAKR1C3HTTALDH1A1 | |
| SCHEMBL8366886 | 0.82 | LMNA (0.51) | MEN1KMT2AAKR1C3MAPTALDH1A1 | |
| SCHEMBL14485676 | 0.81 | HTT (0.70) | MEN1KMT2AAKR1C3MAPTHTT | |
| SCHEMBL7791335 | 0.81 | AKR1C3 (0.54) | MEN1KMT2AAKR1C3MAPTGGPS1 | |
| SCHEMBL7791333 | 0.81 | AKR1C3 (0.54) | MEN1KMT2AAKR1C3MAPTGGPS1 | |
| SCHEMBL27702845 | 0.81 | KDM1A (0.65) | MEN1KMT2AAKR1C3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612378-A | TREATING THROMBOSIS, ISCHEMIA, STROKE, RESTENOSIS OR INFLAMMATION | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996039380-A1 | BIS-ARYLSULFONYLAMINOBENZAMIDE DERIVATIVES AND THE USE THEREOF AS FACTOR Xa INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1996-12-12 | — | — | WO | disclosed |