Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322835 | 0.95 | MEN1 (0.58) | MEN1KMT2AAKR1C3F2F10 | |
| SCHEMBL8366277 | 0.90 | MEN1 (0.49) | MEN1KMT2AAKR1C3F2F10 | |
| Hydrochloric Acid SCHEMBL8368784 | 0.87 | HTR6 (0.65) | MEN1KMT2AHTR6MAPTCFD | |
| SCHEMBL8364289 | 0.85 | RAB9A (0.49) | MEN1KMT2AAKR1C3HTR6MAPT | |
| SCHEMBL7316591 | 0.81 | AKR1C3 (0.58) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL7323404 | 0.81 | AKR1C3 (0.58) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8364333 | 0.80 | AKR1C3 (0.53) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8366229 | 0.80 | AKR1C3 (0.53) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8367782 | 0.80 | SMN1; SMN2 (0.75) | MEN1KMT2AAKR1C3HTTALDH1A1 | |
| SCHEMBL27982973 | 0.79 | TPSAB1 (0.58) | MEN1KMT2AHTR6CYP19A1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741819-A | THROMBOSIS INHIBITORS; ANTIINFLAMMATORY AGENTS; NEURODEGENERATIVE DISORDERS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |