Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322905 | 1.00 | CTSD (0.51) | CTSDRENCSNK1ELAP3ANPEP | |
| SCHEMBL7331822 | 0.83 | CSNK1E (0.46) | CTSDCSNK1ELAP3ANPEPRNPEP | |
| SCHEMBL7328595 | 0.82 | CTSD (0.65) | CTSDREN | |
| SCHEMBL16312273 | 0.81 | CTSD (0.66) | CTSDRENANPEPKLK5 | |
| SCHEMBL16312279 | 0.81 | CTSD (0.65) | CTSDREN | |
| SCHEMBL17776311 | 0.80 | CTSD (0.56) | CTSDREN | |
| SCHEMBL4070035 | 0.80 | MMP2 (0.57) | CTSDRENCSNK1ELAP3ANPEP | |
| SCHEMBL5808622 | 0.79 | LAP3 (0.60) | CTSDLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL21570174 | 0.79 | LAP3 (0.60) | CTSDLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL21570176 | 0.79 | LAP3 (0.60) | CTSDLAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |