Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000388 | 0.83 | MAPK1 (0.36) | L3MBTL1ATMMTNR1AMTNR1BCA4 | |
| SCHEMBL11004704 | 0.83 | MAPK1 (0.36) | L3MBTL1ATMMTNR1AMTNR1BCA4 | |
| SCHEMBL10365895 | 0.82 | ALDH1A3 (0.37) | ALDH1A3KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL19876788 | 0.80 | PPARG (0.34) | L3MBTL1MTNR1AMTNR1BGAAKMT2A | |
| SCHEMBL9490507 | 0.77 | ATM (0.38) | L3MBTL1ATMMTNR1AMTNR1BCA4 | |
| SCHEMBL11005849 | 0.77 | KCNN4 (0.34) | KMT2AMEN1ALDH1A1PPARGPPARA | |
| SCHEMBL11002077 | 0.77 | PPARG (0.38) | CYP1A2CYP2C19KMT2AMEN1PPARG | |
| SCHEMBL9569520 | 0.76 | ATM (0.30) | L3MBTL1ATM | |
| Biphenyl SCHEMBL28762568 | 0.74 | ALDH1A1 (0.35) | L3MBTL1ATMGAACYP1A2CYP2C9 | |
| SCHEMBL11003972 | 0.74 | PPARG (0.38) | KMT2AMEN1PPARGPPARACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-B1 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD (CH) | 1994-03-16 | — | — | EP | disclosed |
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |