SCHEMBL9490507

SCHEMBL9490507

CC(C)(C)C=CC(Oc1ccccc1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA4 P22748 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SLC6A4 P31645 1/20 0.31
METAP1 P53582 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
LTA4H P09960 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7322935 0.77 L3MBTL1 (0.40) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL8733234 0.69 CA4 (0.42) ATML3MBTL1CA4ALDH1A1LMNA
SCHEMBL9638074 0.68 ATM (0.32) ATML3MBTL1MEN1KMT2AMTNR1A
SCHEMBL8718949 0.67 ATM (0.40) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL14463423 0.67 ATM (0.40) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL11911977 0.67 ATM (0.40) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL4739360 0.66 ATM (0.43) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL295469 0.66 ATM (0.43) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL11004704 0.66 MAPK1 (0.36) ATML3MBTL1CA4MEN1ALDH1A1
SCHEMBL11000388 0.66 MAPK1 (0.36) ATML3MBTL1CA4MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370868-B1 USE OF MODIFIED DIORGANOPOLYSILOXANES AS ANTIOXIDANTS IN COSMETICS OR DERMATOLOGY L'OREAL (FR) 1993-03-03 EP disclosed
EP-0370868-A1 Use of modified diorganopolysiloxanes as antioxidants in cosmetics or dermatology L'OREAL (FR) 1990-05-30 EP disclosed