Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | GPR34 | Q9UPC5 | 7/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322984 | 1.00 | PPARG (0.55) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL18862971 | 0.88 | ALDH1A1 (0.52) | MMP9MMP8MME | |
| SCHEMBL6927025 | 0.88 | ALDH1A1 (0.52) | MMP9MMP8MME | |
| SCHEMBL10538691 | 0.88 | ALDH1A1 (0.52) | MMP9MMP8MME | |
| SCHEMBL13537631 | 0.86 | BCL2 (0.58) | PPARGACEPPARA | |
| SCHEMBL8814267 | 0.83 | LDHA (0.49) | MMP9MMP8 | |
| SCHEMBL8814268 | 0.83 | LDHA (0.49) | MMP9MMP8 | |
| SCHEMBL16333610 | 0.81 | CTSK (0.44) | MMP9MMP8 | |
| SCHEMBL10944953 | 0.81 | TACR1 (0.57) | — | |
| SCHEMBL30515231 | 0.81 | TACR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492910-A | AIDS TREATMENT | BRISTOL-MYERS SQUIBB CO. (US) | 1996-02-20 | — | — | US | disclosed |