Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319074 | 0.89 | GPR119 (0.45) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL7384022 | 0.78 | NR1H2 (0.46) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL6749438 | 0.77 | NR1H2 (0.45) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL23849943 | 0.76 | DPP4 (0.46) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL9891005 | 0.76 | NR1H2 (0.44) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL7385084 | 0.76 | KDM4E (0.46) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL8634128 | 0.76 | KDM4E (0.46) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL28646412 | 0.76 | DPP4 (0.46) | GPR119HPGDKDM4EPKMFAAH | |
| SCHEMBL29056036 | 0.73 | FPR2 (0.50) | GPR119HPGDKDM4EPKMTP53 | |
| SCHEMBL16698964 | 0.73 | MEN1 (0.46) | GPR119HPGDKDM4EPKMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889023-A | 3(R)-(2-(PIPERIDIN-4-YL)ETHYL)-2-PIPERIDON-1-YLACETYL-3(S)-3-( PYRIDYL)-BETA-ALANINE OR SALT USED AS AN ANTICOAGULANT | MERCK & CO., INC. (US) | 1999-03-30 | — | — | US | disclosed |