Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAX | P61244 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475263 | 0.86 | ACHE (0.62) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL13271195 | 0.83 | ACHE (0.75) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL20272058 | 0.80 | ACHE (0.69) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL20475283 | 0.79 | ACHE (0.62) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL3181469 | 0.79 | ACHE (1.00) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL13271231 | 0.78 | ACHE (0.65) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL7326602 | 0.76 | ACHE (0.56) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL23612583 | 0.75 | ACHE (0.67) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL3244933 | 0.75 | ALDH1A1 (0.71) | ACHEMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL31011404 | 0.75 | ALDH1A1 (0.71) | ACHEMAPTKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568675-A | HYPOTENSIVE AGENT | E. R. SQUIBB & SONS, INC. (US) | 1986-02-04 | — | — | US | disclosed |