Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434429 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MEN1NPY2RKMT2A | |
| SCHEMBL7324580 | 0.81 | KDM4E (0.54) | CHRM3CHRM2CHRM1ALDH1A1TSHR | |
| SCHEMBL9872975 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MEN1NPY2RKMT2A | |
| SCHEMBL7648878 | 0.74 | ATM (0.65) | CHRM3CHRM2CHRM1ALDH1A1KEAP1 | |
| SCHEMBL28205306 | 0.73 | KEAP1 (0.50) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL7319884 | 0.72 | CYP2D6 (0.64) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL9809511 | 0.72 | KEAP1 (0.72) | CHRM3CHRM2CHRM1ALDH1A1KEAP1 | |
| SCHEMBL3051018 | 0.72 | KEAP1 (0.72) | CHRM3CHRM2CHRM1ALDH1A1KEAP1 | |
| SCHEMBL14032807 | 0.72 | LMNA (0.58) | ALDH1A1MEN1NPY2RKMT2A | |
| SCHEMBL7323613 | 0.72 | ALDH1A1 (0.56) | ALDH1A1NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |