Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPA2 | P48052 | 2/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323423 | 0.90 | TACR3 (0.36) | ANPEPLTA4H | |
| SCHEMBL7321472 | 0.90 | CA12 (0.37) | ANPEPCPA1CPA2CPA4ACE2 | |
| SCHEMBL7326674 | 0.89 | MME (0.36) | ANPEPCPA1CPA2CPA4ACE2 | |
| SCHEMBL7322317 | 0.87 | MMP1 (0.47) | — | |
| SCHEMBL7328790 | 0.87 | SLC1A3 (0.44) | ACE2MMEECE1 | |
| SCHEMBL7320171 | 0.85 | CPA1 (0.41) | ANPEPCPA1CPA2CPA4ACE2 | |
| SCHEMBL6412346 | 0.82 | CPA1 (0.45) | CPA1CPA2CPA4ACE2CPB1 | |
| SCHEMBL6917414 | 0.82 | MMP1 (0.41) | CPA1CPA2CPA4ACE2CPB1 | |
| SCHEMBL6417816 | 0.80 | ECE1 (0.40) | CPA1CPA2CPA4ACE2CPB1 | |
| SCHEMBL6412734 | 0.79 | CPA1 (0.39) | CPA1CPA2CPA4ACE2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |