Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.47 |
| ▸ | MMP3 | P08254 | 15/20 | 0.47 |
| ▸ | MMP9 | P14780 | 14/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321038 | 0.91 | MMP1 (0.49) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7323541 | 0.87 | ANPEP (0.38) | — | |
| SCHEMBL7323423 | 0.84 | TACR3 (0.36) | MMP9MMP2 | |
| SCHEMBL7321472 | 0.84 | CA12 (0.37) | — | |
| SCHEMBL7326674 | 0.83 | MME (0.36) | — | |
| SCHEMBL7323291 | 0.83 | MMP9 (0.52) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7323279 | 0.83 | MMP9 (0.52) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7323303 | 0.83 | MMP9 (0.52) | MMP1MMP3MMP9MMP2 | |
| SCHEMBL7328790 | 0.81 | SLC1A3 (0.44) | — | |
| SCHEMBL7320171 | 0.79 | CPA1 (0.41) | MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |