Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 8/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328692 | 0.83 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL10376838 | 0.83 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL7807953 | 0.83 | CTSD (0.63) | TRPM8CTSDCTSBCTSKREN | |
| SCHEMBL7807985 | 0.83 | CTSD (0.56) | TRPM8CTSDCTSBCTSKREN | |
| SCHEMBL7329749 | 0.82 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL7322916 | 0.82 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL8945246 | 0.81 | CTSD (0.53) | CTSDREN | |
| SCHEMBL9095899 | 0.81 | CTSD (0.53) | CTSDREN | |
| SCHEMBL3210676 | 0.81 | CTSB (0.60) | TRPM8CTSDCTSBCTSKECE1 | |
| SCHEMBL13823620 | 0.81 | CTSB (0.60) | TRPM8CTSDCTSBCTSKECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |