Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 16/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376838 | 1.00 | CTSD (0.54) | CTSDANPEPKLK5PSEN1PSEN2 | |
| SCHEMBL7323581 | 0.83 | TRPM8 (0.55) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL7329749 | 0.83 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL7322916 | 0.83 | CTSD (0.54) | CTSDKLK5PSEN1PSEN2APH1B | |
| SCHEMBL3202559 | 0.80 | CTSD (0.69) | CTSDANPEP | |
| SCHEMBL8894290 | 0.77 | CTSD (0.66) | CTSDANPEP | |
| SCHEMBL463955 | 0.76 | KLK5 (0.54) | CTSDANPEPKLK5 | |
| SCHEMBL7329133 | 0.75 | PSEN1 (0.58) | CTSDKLK5PSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL7348250 | 0.75 | LAP3 (0.44) | ANPEP | |
| SCHEMBL16312279 | 0.74 | CTSD (0.65) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |