Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323689 | 1.00 | TNFRSF1A (0.64) | TNFRSF1AABCG2ABCB1MAPTKMT2A | |
| SCHEMBL7330202 | 0.94 | TNFRSF1A (0.58) | TNFRSF1AABCG2ABCB1MAPTKMT2A | |
| SCHEMBL9065919 | 0.83 | HTR1A (0.60) | TNFRSF1AABCG2MAPTKMT2ANPC1 | |
| SCHEMBL9065922 | 0.83 | HTR1A (0.60) | TNFRSF1AABCG2MAPTKMT2ANPC1 | |
| SCHEMBL29823386 | 0.83 | HTR1A (0.60) | TNFRSF1AABCG2MAPTKMT2ANPC1 | |
| SCHEMBL17301255 | 0.82 | HTR1A (0.60) | TNFRSF1AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7338984 | 0.80 | PLAU (0.63) | MAPTKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7855954 | 0.80 | KMT2A (0.61) | TNFRSF1AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL29823740 | 0.80 | KMT2A (0.61) | TNFRSF1AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7855955 | 0.80 | KMT2A (0.61) | TNFRSF1AMAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |