SCHEMBL7855955

SCHEMBL7855955

COc1cc(C=O)ccc1OC(=O)C=Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.61
▸ HTR1A P08908 1/20 0.58
▸ TTR P02766 2/20 0.56
▸ TNFRSF1A P19438 1/20 0.56
▸ ALDH1A1 P00352 5/20 0.55
▸ TSHR P16473 1/20 0.55
▸ CYP1A1 P04798 1/20 0.55
▸ CYP1A2 P05177 1/20 0.55
▸ CYP1B1 Q16678 1/20 0.55
▸ KDM4E B2RXH2 4/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.55
▸ HPGD P15428 1/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ MAPK1 P28482 1/20 0.55
▸ HSD17B10 Q99714 1/20 0.55
▸ NPC1 O15118 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ RAB9A P51151 2/20 0.54
▸ JUN P05412 1/20 0.53
▸ NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7855954 1.00 KMT2A (0.61) KMT2AHTR1ATTRTNFRSF1AALDH1A1
SCHEMBL29823740 1.00 KMT2A (0.61) KMT2AHTR1ATTRTNFRSF1AALDH1A1
SCHEMBL13231236 0.89 KMT2A (0.56) KMT2AALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL27220248 0.89 KMT2A (0.61) KMT2ATNFRSF1AALDH1A1TSHRKDM4E
SCHEMBL27220263 0.88 KMT2A (0.55) KMT2AALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL27220142 0.88 ABCG2 (0.59) KMT2AALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL27220187 0.87 NQO2 (0.60) KMT2AHTR1ATTRALDH1A1TSHR
SCHEMBL27220272 0.86 ALDH1A1 (0.54) KMT2AALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL27220289 0.86 ALDH1A1 (0.52) KMT2AALDH1A1TSHRCYP1A2KDM4E
SCHEMBL17301255 0.86 HTR1A (0.60) KMT2AHTR1ATNFRSF1AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987551-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. 2024-05-21 — — US claimed
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2022-07-28 — — US claimed
US-12637409-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. (US) 2026-05-26 — — US disclosed
US-20240317670-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2024-09-26 — — US disclosed
US-20240300883-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2024-09-12 — — US disclosed
US-11987551-B2 Styryl carboxylate derivatives Renovel Innovations, Inc. 2024-05-21 — — US disclosed
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES Renovel Innovations, Inc. 2022-07-28 — — US disclosed
US-20140302218-A1 PRESERVATIVE COMBINATIONS PURAC BIOCHEM B.V. (NL) 2014-10-09 — — US disclosed
CN-104039176-A Preservative composition PURAC BIOCHEM BV 2014-09-10 — — CN disclosed
EP-2768326-A1 PRESERVATIVE COMBINATIONS Purac Biochem bv (NL) 2014-08-27 — — EP disclosed
WO-2013058651-A1 PRESERVATIVE COMBINATIONS PURAC BIOCHEM B.V. (NL) 2013-04-25 — — WO disclosed
EP-2583568-A1 Preservative combinations comprising vanillin and cinnamic acid Purac Biochem N.V. (NL) 2013-04-24 — — EP disclosed
JP-2001103933-A MIXED FOOD AND FEED ADDITIVE EACH CONTAINING SPORE OF BRACKET FUNGUS OF GENUS FOMES TANAKA TOMOJI 2001-04-17 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220234987-A1 STYRYL CARBOXYLATE DERIVATIVES ACACB, ACACA, FABP7 KMT2A 1056/4885HTR1A 2749/4885TTR 3313/4885
US-20240300883-A1 STYRYL CARBOXYLATE DERIVATIVES SCD, ACACB, ACACA KMT2A 780/4885HTR1A 3716/4885TTR 2918/4885
US-20240317670-A1 STYRYL CARBOXYLATE DERIVATIVES ACACB, ACACA, GPR119 KMT2A 995/4885HTR1A 2753/4885TTR 3459/4885
US-12637409-B2 Styryl carboxylate derivatives GPR119, ACACB, ACACA KMT2A 778/4885HTR1A 2818/4885TTR 4381/4885
US-11987551-B2 Styryl carboxylate derivatives ACACB, ACACA, FABP7 KMT2A 1056/4885HTR1A 2749/4885TTR 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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