Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065919 | 1.00 | HTR1A (0.60) | HTR1AESR1ESR2KMT2AMEN1 | |
| SCHEMBL9065922 | 1.00 | HTR1A (0.60) | HTR1AESR1ESR2KMT2AMEN1 | |
| SCHEMBL17301255 | 0.86 | HTR1A (0.60) | HTR1AKMT2AMEN1TNFRSF1AMMP1 | |
| SCHEMBL9284213 | 0.86 | MAPT (0.58) | HTR1AKMT2APOLBLMNAHTT | |
| SCHEMBL29823458 | 0.84 | NFE2L2 (0.57) | HTR1AESR1ESR2KMT2AMEN1 | |
| SCHEMBL7855954 | 0.84 | KMT2A (0.61) | HTR1AKMT2AMEN1TNFRSF1AMAPT | |
| SCHEMBL29823740 | 0.84 | KMT2A (0.61) | HTR1AKMT2AMEN1TNFRSF1AMAPT | |
| SCHEMBL7855955 | 0.84 | KMT2A (0.61) | HTR1AKMT2AMEN1TNFRSF1AMAPT | |
| SCHEMBL7323689 | 0.83 | TNFRSF1A (0.64) | HTR1AKMT2AMEN1TNFRSF1AMMP1 | |
| SCHEMBL7323696 | 0.83 | TNFRSF1A (0.64) | HTR1AKMT2AMEN1TNFRSF1AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220234987-A1 | STYRYL CARBOXYLATE DERIVATIVES | Renovel Innovations, Inc. | 2022-07-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220234987-A1 | STYRYL CARBOXYLATE DERIVATIVES | ACACB, ACACA, FABP7 | HTR1A 2749/4885ESR1 3111/4885ESR2 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.