SCHEMBL732374

SCHEMBL732374

C(OCC1CO1)C1CO1.OC1CCCC1O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 6/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 1/20 0.43
TP53 P04637 2/20 0.42
CYP3A4 P08684 2/20 0.42
HIF1A Q16665 1/20 0.31
MGLL Q99685 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730829 0.95 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28812806 0.95 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL733108 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL730237 0.83 TSHR (0.50) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Cyclohexanol SCHEMBL28034283 0.80 TSHR (0.52) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28515263 0.80 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Cyclopropane SCHEMBL963062 0.80 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Hydrogen Peroxide SCHEMBL27921718 0.80 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Cyclohexane SCHEMBL960269 0.80 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL8044179 0.80 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9624380-B2 Sulfide extended epoxy resins and barrier coating applications thereof SUN CHEMICAL CORPORATION (US) 2017-04-18 US disclosed
US-20140342091-A1 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATING APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2014-11-20 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
EP-2788398-A2 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF Sun Chemical Corporation (US) 2014-10-15 EP disclosed
US-8765984-B2 Methods and systems for making thiol compounds from terminal olefinic compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-07-01 US disclosed
WO-2013090702-A2 SULFIDE EXTENDED EPOXY RESINS AND BARRIER COATINGS APPLICATIONS THEREOF SUN CHEMICAL CORPORATION (US) 2013-06-20 WO disclosed
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-09-13 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
US-7910666-B2 Mercaptan-hardened epoxy polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-03-22 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
WO-2009132010-A1 METHODS AND SYSTEMS FOR MAKING THIOL COMPOUNDS FROM TERMINAL OLEFINIC COMPOUNDS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-29 WO disclosed
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-10-22 US disclosed
EP-1940992-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070112100-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-05-17 US disclosed
WO-2007022217-A1 MERCAPTAN-HARDENED EPOXY POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232297-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885SMN1; SMN2 4271/4885ALDH1A1 157/4885
US-20090264669-A1 Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds TST, HHAT, GSTO1 TSHR 4571/4885SMN1; SMN2 4271/4885ALDH1A1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.