Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647536 | 0.81 | CYP1A2 (0.38) | — | |
| SCHEMBL7793571 | 0.79 | — | — | |
| SCHEMBL15521252 | 0.79 | NPC1 (0.34) | ESR2 | |
| SCHEMBL13393068 | 0.78 | — | — | |
| SCHEMBL13460696 | 0.78 | — | — | |
| SCHEMBL21251500 | 0.77 | ADRA2A (0.33) | — | |
| SCHEMBL5864584 | 0.76 | LMNA (0.44) | ESR2 | |
| SCHEMBL14495938 | 0.74 | — | — | |
| SCHEMBL14734472 | 0.73 | ESR2 (0.41) | ESR2 | |
| SCHEMBL12676201 | 0.73 | CES2 (0.39) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470849-A | Anticoagulants | SMITHKLINE BEECHAM CORP. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0557406-A4 | -G(G)-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | — | 1993-10-06 | — | — | EP | disclosed |
| EP-0557406-A1 | GAMMA-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007568-A1 | η-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |