Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.76 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318542 | 0.91 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL395 | 0.86 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL6534771 | 0.85 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL396 | 0.84 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL11092792 | 0.82 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8076001 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9530606 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9088981 | 0.80 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL1076 | 0.80 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL174 | 0.79 | AGTR2 (0.83) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |