Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27560994 | 0.78 | MMP8 (0.56) | ANPEPMMP8ALDH1A1L3MBTL1MMP1 | |
| SCHEMBL10707972 | 0.76 | MMP8 (0.46) | ANPEPMMP8ALDH1A1LAP3RNPEP | |
| SCHEMBL10448519 | 0.74 | ANPEP (0.50) | ANPEPMMP8ALDH1A1L3MBTL1MMP1 | |
| SCHEMBL1792751 | 0.74 | KMT2A (0.59) | ANPEPMMP8ALDH1A1RNPEPDNPEP | |
| SCHEMBL4743866 | 0.74 | KMT2A (0.59) | ANPEPMMP8ALDH1A1RNPEPDNPEP | |
| SCHEMBL22522245 | 0.74 | KMT2A (0.59) | ANPEPMMP8ALDH1A1RNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL10520633 | 0.73 | KMT2A (0.58) | ANPEPMMP8ALDH1A1RNPEPDNPEP | |
| SCHEMBL21233884 | 0.73 | ANPEP (0.56) | ANPEPMMP8ALDH1A1L3MBTL1MMP1 | |
| Trifluoroacetic Acid SCHEMBL10572656 | 0.72 | ANPEP (0.55) | ANPEPMMP8ALDH1A1LAP3RNPEP | |
| SCHEMBL10906077 | 0.72 | CTSK (0.57) | ANPEPMMP8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437508-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990003971-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-04-19 | — | — | WO | disclosed |