SCHEMBL732483

SCHEMBL732483

NCC=CN1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582017 0.97
SCHEMBL4396772 0.75
SCHEMBL4202497 0.75 SMN1; SMN2 (0.37)
SCHEMBL1602300 0.74 TRPA1 (0.32)
SCHEMBL6147013 0.74 HSD17B10 (0.33)
SCHEMBL1602298 0.74 TRPA1 (0.32)
SCHEMBL6147015 0.74 HSD17B10 (0.33)
SCHEMBL45553 0.72 LTA4H (0.39)
SCHEMBL3281206 0.70 TRPA1 (0.33)
SCHEMBL2373374 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105717756-B Semi-aqueous photoresist or semiconductor manufacturing residue stripping and cleaning compositions with improved silicon passivation 弗萨姆材料美国有限责任公司 2021-02-02 CN claimed
CN-109415538-B Use of additive composition for preparing polycondensation polymer 科莱恩塑料和涂料有限公司 2022-03-01 CN disclosed
CN-105717756-B Semi-aqueous photoresist or semiconductor manufacturing residue stripping and cleaning compositions with improved silicon passivation 弗萨姆材料美国有限责任公司 2021-02-02 CN disclosed
US-8377935-B2 Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase JANSSEN PHARMACEUTICA N.V. (BE) 2013-02-19 US disclosed
US-8138198-B2 Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase ANGIBAUD PATRICK RENE (FR) 2012-03-20 US disclosed
EP-1453805-B1 4-PIPERIDINYL ALKYLAMINE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS HOFFMANN LA ROCHE (CH) 2010-12-22 EP disclosed
US-20090221580-A1 Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase ANGIBAUD PATRICK RENE 2009-09-03 US disclosed
US-5470851-A Antihistamine, anticoagulants SANKYO COMPANY, LIMITED (JP) 1995-11-28 US disclosed
EP-0463873-A1 Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use Sankyo Company Limited (JP) 1992-01-02 EP disclosed
US-4835157-A Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents ORTHO PHARMACEUTICAL CORPORATION (US) 1989-05-30 US disclosed
US-4675403-A SIDE EFFECT REDUCTION AMERICAN HOME PRODUCTS CORPORATION (US) 1987-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221580-A1 Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase HDAC1, HDAC2, HDAC3 CA1 3871/4885CA2 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.