Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.76 |
| ▸ | MMP1 | P03956 | 11/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.75 |
| ▸ | PGR | P06401 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | APEX1 | P27695 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | IKBKB | O14920 | 1/20 | 0.73 |
| ▸ | CHUK | O15111 | 1/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15671680 | 1.00 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL2898449 | 1.00 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL5912759 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Water SCHEMBL201856 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL2123848 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3126388 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL1301198 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3836633 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Dexamethasone SCHEMBL3404392 | 0.95 | HIF1A (0.82) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL11064010 | 0.94 | NR3C1 (0.72) | NR3C1MMP1CYP3A4PGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7177 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121490062-B | Dexamethasone-containing composition and application thereof in preparation of medicament for treating retinopathy | 上饶爱尔眼科医院有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20260108657-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS | INSIGNIA PHARMACEUTICALS, LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-12551148-B2 | Systems and methods for compensating for agent elution | MEDTRONIC MINIMED, INC. (US) | 2026-02-17 | — | — | US | claimed |
| US-20260021113-A1 | INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE | EYEDEA BIO LLC (US) | 2026-01-22 | — | — | US | claimed |
| US-12491289-B2 | Pharmaceutical compositions for treating osteoarthritis | INSIGNIA PHARMACEUTICALS, LLC (US) | 2025-12-09 | — | — | US | claimed |
| EP-4654956-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS | Insignia Pharmaceuticals, LLC (US) | 2025-12-03 | — | — | EP | claimed |
| US-12433900-B2 | Intravitreal corticosteroid extended release implant and methods of use | EYEDEA BIO, LLC (US) | 2025-10-07 | — | — | US | claimed |
| US-20250295608-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS | INSIGNIA PHARMACEUTICALS, LLC (US) | 2025-09-25 | — | — | US | claimed |
| US-20250288599-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS | INSIGNIA PHARMACEUTICALS, LLC (US) | 2025-09-18 | — | — | US | claimed |
| US-20250275916-A1 | MEDICATED EYELID CLEANSING COMPOSITIONS | OCUSOFT, INC. | 2025-09-04 | — | — | US | claimed |
| CN-1073859-A | Regulate the compositions of wrinkle of skin and/or atrophoderma | RICHARDSON VICKS INC (US) | 1993-07-07 | — | — | CN | claimed |
| WO-1993010756-A1 | USE OF SALICYLIC ACID FOR REGULATING SKIN WRINKLES AND/OR SKIN ATROPHY | RICHARDSON-VICKS, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| WO-1993010755-A1 | COMPOSITIONS FOR REGULATING SKIN WRINKLES AND/OR SKIN ATROPHY | RICHARDSON-VICKS, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| EP-0538368-A1 | MINIATURE STEROID ELUTING PACING LEAD ELECTRODE | MEDTRONIC, INC. (US) | 1993-04-28 | — | — | EP | claimed |
| WO-1991019533-A1 | MINIATURE STEROID ELUTING PACING LEAD ELECTRODE | MEDTRONIC, INC. (US) | 1991-12-26 | — | — | WO | claimed |
| EP-0126684-B1 | DRUG DELIVERY SYSTEM UTILIZING THERMOSETTING GELS | MERCK & CO. INC. (US) | 1991-08-28 | — | — | EP | claimed |
| US-4506680-A | Drug dispensing body implantable lead | MEDTRONIC, INC. (US) | 1985-03-26 | — | — | US | claimed |
| US-4346709-A | Drug delivery devices comprising erodible polymer and erosion rate modifier | ALZA CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
| EP-0056420-A1 | Ophthalmic gel | SCHERING CORPORATION (US) | 1982-07-28 | — | — | EP | claimed |
| US-4255415-A | COMPRISING A MEDICAMENT, A VINYL ACETATE-VINYL ALCOHOL COPOLYMER, AN ALKALI OR ALKALINE BORATE, AND STERILE WATER; TOPICAL | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | claimed |