Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.76 |
| ▸ | MMP1 | P03956 | 11/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.75 |
| ▸ | PGR | P06401 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | AR | P10275 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | APEX1 | P27695 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | IKBKB | O14920 | 1/20 | 0.73 |
| ▸ | CHUK | O15111 | 1/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15671680 | 1.00 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL73249 | 1.00 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL5912759 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Water SCHEMBL201856 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL2123848 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3126388 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL1301198 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3836633 | 0.99 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Dexamethasone SCHEMBL3404392 | 0.95 | HIF1A (0.82) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL11064010 | 0.94 | NR3C1 (0.72) | NR3C1MMP1CYP3A4PGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10080785-B2 | Albumin fusion proteins | NOVOZYMES BIOPHARMA DK A/S (DK) | 2018-09-25 | — | — | US | disclosed |
| US-20180200346-A1 | ALBUMIN FUSION PROTEINS | ALBUMEDIX A/S (DK) | 2018-07-19 | — | — | US | disclosed |
| US-9983196-B2 | Compositions and methods for optimizing drug hydrophobicity and drug delivery to cells | BIOELASTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-9849162-B2 | Treatment with factor VII-albumin fusion protein | ALBUMEDIX A/S (DK) | 2017-12-26 | — | — | US | disclosed |
| US-9821039-B2 | Albumin fusion proteins | ALBUMEDIX A/S (DK) | 2017-11-21 | — | — | US | disclosed |
| US-9775888-B2 | Treatment with factor ix-albumin fusion protein | ALBUMEDIX A/S (DK) | 2017-10-03 | — | — | US | disclosed |
| US-20170096472-A1 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. | 2017-04-06 | — | — | US | disclosed |
| US-20160152687-A1 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. | 2016-06-02 | — | — | US | disclosed |
| US-9296809-B2 | Albumin fusion proteins | HUMAN GENOME SCIENCES, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| EP-2990417-A1 | ALBUMIN INSULIN FUSION PROTEIN | Human Genome Sciences, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| WO-2001055367-A1 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001053530-A1 | HUMAN PROTEIN TYROSINE PHOSPHATASE POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-07-26 | — | — | WO | disclosed |
| EP-0197718-B2 | New medicaments for topical use | FIDIA SPA (IT) | 2001-07-25 | — | — | EP | disclosed |
| WO-2001051504-A1 | 71 HUMAN SECRETED PROTEINS | HUMAN GENOME SCIENCES, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001046254-A1 | TRANSFERRIN POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001046475-A1 | TREFOIL DOMAIN-CONTAINING POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001046255-A1 | NK CELL RECEPTOR POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| EP-0197718-B1 | New medicaments for topical use | FIDIA SPA (IT) | 1993-12-15 | — | — | EP | disclosed |
| EP-0555898-A2 | Medicaments for non-topical use | FIDIA S.p.A. (IT) | 1993-08-18 | — | — | EP | disclosed |
| EP-0197718-A2 | New medicaments for topical use | FIDIA S.p.A. (IT) | 1986-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180200346-A1 | ALBUMIN FUSION PROTEINS | ALB, FABP1, HDGF | NR3C1 3057/4885MMP1 2327/4885CYP3A4 4376/4885 |
| US-20160152687-A1 | ALBUMIN FUSION PROTEINS | ALB, FABP1, HDGF | NR3C1 3057/4885MMP1 2327/4885CYP3A4 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.