Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.75 |
| ▸ | MMP1 | P03956 | 11/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.74 |
| ▸ | PGR | P06401 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | IKBKB | O14920 | 1/20 | 0.72 |
| ▸ | CHUK | O15111 | 1/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123848 | 1.00 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3126388 | 1.00 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL3836633 | 1.00 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL5912759 | 1.00 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL73249 | 0.99 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL2898449 | 0.99 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL15671680 | 0.99 | NR3C1 (0.76) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Water SCHEMBL201856 | 0.98 | NR3C1 (0.75) | NR3C1MMP1CYP3A4PGRMEN1 | |
| Dexamethasone SCHEMBL3404392 | 0.95 | HIF1A (0.82) | NR3C1MMP1CYP3A4PGRMEN1 | |
| SCHEMBL11064010 | 0.94 | NR3C1 (0.72) | NR3C1MMP1CYP3A4PGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107532201-B | Method for assessing response of patients with ataxia telangiectasia to glucocorticoid therapy | 爱瑞德勒股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| US-20150297588-A1 | STERILE OTIC FORMULATIONS | Entrx LLC | 2015-10-22 | — | — | US | claimed |
| US-5942276-A | Method of manufacturing x-ray visible soluble covering | MEDTRONIC, INC. (US) | 1999-08-24 | — | — | US | claimed |
| JP-11279065-A | — | — | None | — | — | JP | disclosed |
| US-20250332427-A1 | ELECTRODES FOR INTRA-CARDIAC PACEMAKER | MEDTRONIC INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12350502-B2 | Electrodes for intra-cardiac pacemaker | MEDTRONIC, INC. (US) | 2025-07-08 | — | — | US | disclosed |
| US-20250161213-A1 | OIL-IN-WATER EMULSION WITH AGAR AND DIACETYL TARTARIC ACID ESTERS OF MONO-AND DI-GLYCERIDES (DATEM) | VITUX GROUP AS (NO) | 2025-05-22 | — | — | US | disclosed |
| EP-4486306-A1 | OIL-IN-WATER EMULSION WITH AGAR AND DIACETYL TARTARIC ACID ESTERS OF MONO-AND DI-GLYCERIDES (DATEM) | Vitux Group AS (NO) | 2025-01-08 | — | — | EP | disclosed |
| US-12011450-B2 | Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2024-06-18 | — | — | US | disclosed |
| US-20240180828-A1 | COMPOSITIONS | VITUX GROUP AS (NO) | 2024-06-06 | — | — | US | disclosed |
| US-20240165130-A1 | COMPOSITE DRUG PARTICLES AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-05-23 | — | — | US | disclosed |
| EP-0138347-B1 | AN IONTOPHORESIS DEVICE | KABUSHIKI KAISYA ADVANCE (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0308572-A2 | An iontophoresis device | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1989-03-29 | — | — | EP | disclosed |
| US-4764164-A | Iontophoresis device | KABUSHIKI KAISYA ADVANCE KAIHATSU KENKYUJO (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0253901-A1 | SUSTAINED-RELEASE PREPARATION | TEIJIN LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-H356-H | EPICARDIAL LEAD HAVING LOW THRESHOLD, LOW POLARIZATION MYOCARDIAL ELECTRODE | MEDTRONIC, INC. (US) | 1987-11-03 | — | — | US | disclosed |
| US-4577642-A | Drug dispensing body implantable lead employing molecular sieves and methods of fabrication | MEDTRONIC, INC. (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0171084-A2 | Pharmaceutical oil-in-water type micro-emulsion | LEDERLE (JAPAN) LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0138347-A1 | An iontophoresis device | KABUSHIKI KAISYA ADVANCE (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4112073-A | Medicinal composition comprising adrenal cortical hormone and thyroid stimulating hormone releasing hormone | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240165130-A1 | COMPOSITE DRUG PARTICLES AND USES THEREOF | LIPC, LIPA, FABP4 | NR3C1 108/4885MMP1 1358/4885CYP3A4 193/4885 |
| US-12011450-B2 | Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof | NR3C1, SSB, SERPINA6 | NR3C1 1/4885MMP1 1755/4885CYP3A4 1703/4885 |
| US-20150297588-A1 | STERILE OTIC FORMULATIONS | IFNG, SPOUT1, IL1A | NR3C1 3414/4885MMP1 460/4885CYP3A4 3016/4885 |
| US-20250161213-A1 | OIL-IN-WATER EMULSION WITH AGAR AND DIACETYL TARTARIC ACID ESTERS OF MONO-AND DI-GLYCERIDES (DATEM) | DAGLA, DAGLB, MGLL | NR3C1 3262/4885MMP1 1187/4885CYP3A4 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.