Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328327 | 0.84 | ABCC9 (0.43) | ABCC9IDO1HPGD | |
| SCHEMBL9195110 | 0.83 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9195128 | 0.83 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9195123 | 0.83 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9869526 | 0.81 | SMN1; SMN2 (0.39) | ABCC9CNR2IDO1KCNA5 | |
| SCHEMBL9869515 | 0.81 | SMN1; SMN2 (0.39) | ABCC9CNR2IDO1KCNA5 | |
| SCHEMBL9313743 | 0.80 | ACHE (0.38) | ABCC9IDO1 | |
| SCHEMBL482263 | 0.80 | ABCC9 (0.49) | ABCC9CNR2NPC1RAB9ACNR1 | |
| SCHEMBL482265 | 0.80 | ABCC9 (0.49) | ABCC9CNR2NPC1RAB9ACNR1 | |
| SCHEMBL4715927 | 0.80 | ABCC9 (0.49) | ABCC9CNR2NPC1RAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355565-A1 | 6-Benzoyl-substituted 3,4-dihydro-2H-benzopyranes, method for their preparation and pharmaceutical preparations based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |