Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324904 | 0.84 | ABCC9 (0.51) | ABCC9IDO1HPGD | |
| SCHEMBL9869515 | 0.83 | SMN1; SMN2 (0.39) | ABCC9IDO1 | |
| SCHEMBL9869526 | 0.83 | SMN1; SMN2 (0.39) | ABCC9IDO1 | |
| SCHEMBL9195128 | 0.79 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9195110 | 0.79 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9195123 | 0.79 | ABCC9 (0.40) | ABCC9IDO1 | |
| SCHEMBL9313743 | 0.75 | ACHE (0.38) | ABCC9IDO1 | |
| SCHEMBL7329102 | 0.75 | ABCC9 (0.59) | ABCC9 | |
| SCHEMBL7329096 | 0.75 | ABCC9 (0.59) | ABCC9 | |
| SCHEMBL10638845 | 0.74 | KCNE1 (0.52) | ABCC9IDO1KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355565-A1 | 6-Benzoyl-substituted 3,4-dihydro-2H-benzopyranes, method for their preparation and pharmaceutical preparations based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |