Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255056 | 1.00 | ACE (0.46) | ACEF2FKBP1AHPGDSMN1; SMN2 | |
| SCHEMBL7325895 | 0.83 | PREP (0.44) | F2HPGDSMN1; SMN2 | |
| SCHEMBL7325890 | 0.83 | PREP (0.44) | F2HPGDSMN1; SMN2 | |
| SCHEMBL7324905 | 0.81 | PREP (0.44) | F2HPGDSMN1; SMN2 | |
| SCHEMBL7324911 | 0.81 | PREP (0.44) | F2HPGDSMN1; SMN2 | |
| SCHEMBL9569386 | 0.81 | SLC6A1 (0.41) | ACEHPGDSMN1; SMN2 | |
| SCHEMBL7290559 | 0.81 | SLC6A1 (0.41) | ACEHPGDSMN1; SMN2 | |
| SCHEMBL7282828 | 0.80 | F2 (0.56) | F2FKBP1AHPGD | |
| SCHEMBL9569339 | 0.80 | F2 (0.56) | F2FKBP1AHPGD | |
| SCHEMBL8994559 | 0.76 | ACE (0.46) | ACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-A2 | N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | claimed |