Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325895 | 0.83 | PREP (0.44) | PREPDPP4NPC1TDP1POLB | |
| SCHEMBL7325890 | 0.83 | PREP (0.44) | PREPDPP4NPC1TDP1POLB | |
| SCHEMBL7321743 | 0.81 | F2 (0.50) | HPGDSMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL7324911 | 0.81 | PREP (0.44) | PREPDPP4NPC1TDP1POLB | |
| SCHEMBL7324905 | 0.81 | PREP (0.44) | PREPDPP4NPC1TDP1POLB | |
| SCHEMBL7374895 | 0.80 | CTSK (0.40) | PREPNPC1TAAR1 | |
| SCHEMBL7313161 | 0.79 | ALDH1A1 (0.44) | PREPNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7374733 | 0.78 | F2 (0.46) | PREPNPC1TDP1POLB | |
| SCHEMBL7372462 | 0.75 | MEN1 (0.50) | PREPNPC1 | |
| SCHEMBL8634381 | 0.75 | PREP (0.34) | PREPL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | claimed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |