Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.67 |
| ▸ | HEXB | P07686 | 6/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.64 |
| ▸ | OGA | O60502 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HK1 | P19367 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326626 | 0.90 | HEXA (0.68) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL9626265 | 0.86 | HEXA (0.83) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL9625535 | 0.84 | HEXA (0.81) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL9625395 | 0.84 | HEXA (0.81) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL9625779 | 0.84 | HEXA (0.81) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL9625518 | 0.84 | HEXA (0.81) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL559750 | 0.84 | TDP1 (0.54) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL29773409 | 0.84 | TDP1 (0.54) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL6278202 | 0.83 | HEXA (0.71) | HEXAHEXBSIRT1OGAKMT2A | |
| SCHEMBL1162143 | 0.83 | TDP1 (0.57) | SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |