SCHEMBL559750

SCHEMBL559750

O=CCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GLS O94925 1/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
CHRM2 P08172 2/20 0.53
CYP2D6 P10635 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773409 1.00 TDP1 (0.54) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL1162143 0.94 TDP1 (0.57) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL11682271 0.93 TDP1 (0.60) TDP1L3MBTL1CYP1A2CYP2C19CHRM2
SCHEMBL30601919 0.93 TDP1 (0.60) TDP1L3MBTL1CYP1A2CYP2C19CHRM2
SCHEMBL5818475 0.93 TDP1 (0.60) TDP1L3MBTL1CYP1A2CYP2C19CHRM2
SCHEMBL4580338 0.93 TDP1 (0.60) TDP1L3MBTL1CYP1A2CYP2C19CHRM2
SCHEMBL30185439 0.88 GLS (0.57) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL1042197 0.88 GLS (0.57) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL14605579 0.88 TDP1 (0.44) TDP1L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL7324978 0.84 HEXA (0.67) MAPTRAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410098-A Preparation method for synthesizing alpha-aminoketone compound from fatty aldehyde and secondary amine 西北工业大学 2023-07-11 CN claimed
US-8916605-B2 Compounds and methods for treating cancer and viral infections JUPITER BIOMEDICAL RESEARCH, INC. 2014-12-23 US claimed
CN-102438618-A Compounds and methods for treating cancer and viral infections GOFF HILL LTD 2012-05-02 CN claimed
US-20120035238-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS GOFF HILL LIMITED (BB) 2012-02-09 US claimed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
WO-2026088120-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260062422-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2026-03-05 US disclosed
EP-4419525-B1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LTD (GB) 2025-07-23 EP disclosed
US-20250230165-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LIMITED (GB) 2025-07-17 US disclosed
US-12286434-B2 Pan-tropic entry inhibitors EMORY UNIVERSITY (US) 2025-04-29 US disclosed
US-20240368146-A1 Morpholine-Containing & Piperazine-Containing CXCR4 Modulators and Uses Related Thereto UNIV EMORY (US) 2024-11-07 US disclosed
US-20240293391-A1 ISOQUINOLINE AND PYRIDINE BASED CXCR4 ANTAGONISTS UNIV LEUVEN KATH (BE) 2024-09-05 US disclosed
EP-0376819-A1 Acrylated polyamines, process for their preparation and their use as fungicides ROUSSEL-UCLAF (FR) 1990-07-04 EP disclosed
US-4650810-A OR INDOLE-5-THIOACETAMIDES GLAXO GROUP LIMITED (GB) 1987-03-17 US disclosed
US-4044123-A ANTIBIOTICS SCHERING CORPORATION (US) 1977-08-23 US disclosed
US-4002608-A ANTIBACTERIALS SCHERING CORPORATION (US) 1977-01-11 US disclosed
US-4002742-A 1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor SCHERING CORPORATION (US) 1977-01-11 US disclosed
US-4000261-A 5-EPI-4,6-DI-O-(AMINOGLYCOSYL)-2-DEOXYSTREPTAMINES, METHODS FOR THEIR MANUFACTURE AND INTERMEDIATES USEFUL THEREIN, METHODS FOR THEIR USE AS ANTIBACTERIAL AGENTS AND COMPOSITIONS USEFUL THEREFOR SCHERING CORPORATION (US) 1976-12-28 US disclosed
US-4000262-A 5-EPI-AMINO AND 5-EPI-AZIDO-4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXYSTREPTAMINES 1-N-ALKYL-5-EPI-AMINO AND 1-N-ALKYL-5-EPI-AZIDO-4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXYSTREPTAMINES SCHERING CORPORATION (US) 1976-12-28 US disclosed
US-3974209-A WATER TREATMENT, COMPLEX METAL IONS MONSANTO COMPANY (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368146-A1 Morpholine-Containing & Piperazine-Containing CXCR4 Modulators and Uses Related Thereto CXCR4, CXCL12, MYD88 TDP1 4133/4885L3MBTL1 1862/4885MAPT 3900/4885
US-12286434-B2 Pan-tropic entry inhibitors CXCR4, CCR5, CXCL12 TDP1 1633/4885L3MBTL1 3954/4885MAPT 3119/4885
US-20120035238-A1 COMPOUNDS AND METHODS FOR TREATING CANCER AND VIRAL INFECTIONS TP53, RNASE1, FURIN TDP1 1016/4885L3MBTL1 1644/4885MAPT 1990/4885
US-20260062422-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE BRD4, AR, BRD3 TDP1 2874/4885L3MBTL1 1282/4885MAPT 3710/4885
US-20240293391-A1 ISOQUINOLINE AND PYRIDINE BASED CXCR4 ANTAGONISTS CXCR4, CCR5, CXCR1 TDP1 3385/4885L3MBTL1 2831/4885MAPT 2687/4885
US-20250230165-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER NQO1, VHL, SDHA TDP1 775/4885L3MBTL1 3383/4885MAPT 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.