Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327666 | 0.85 | CHRM1 (0.46) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL7360634 | 0.83 | CHRM1 (0.42) | CHRM1MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7320742 | 0.77 | CHRM1 (0.42) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL4730348 | 0.75 | CHRM1 (0.53) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL12306789 | 0.75 | PRKCD (0.65) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL4782353 | 0.73 | CHRM1 (0.52) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL7325008 | 0.73 | CHRM1 (0.45) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL2909501 | 0.73 | CHRM1 (0.49) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL7325041 | 0.73 | ROCK2 (0.36) | CHRM1ROCK2ROCK1PRKCEPRKCD | |
| SCHEMBL2909374 | 0.72 | CHRM1 (0.44) | CHRM1ROCK2ROCK1PRKCEPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287696-B1 | ISOQUINOLINE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0287696-A1 | Isoquinoline derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-10-26 | — | — | EP | disclosed |