Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.61 |
| ▸ | CTSB | P07858 | 8/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366989 | 0.90 | CTSL (0.62) | CTSLCTSBCTSKCTSS | |
| SCHEMBL30404224 | 0.90 | CTSL (0.62) | CTSLCTSBCTSKCTSS | |
| SCHEMBL3881009 | 0.90 | CTSL (0.62) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7326168 | 0.90 | CTSL (0.55) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7351619 | 0.87 | CTSL (0.58) | CTSLCTSBCTSKCTSS | |
| SCHEMBL2747500 | 0.85 | MGLL (0.51) | CTSL | |
| SCHEMBL6473095 | 0.85 | CTSL (0.62) | CTSLCTSBCTSKCTSS | |
| SCHEMBL8432473 | 0.84 | CTSL (0.65) | CTSLCTSBCTSKCTSS | |
| SCHEMBL8432468 | 0.84 | CTSL (0.65) | CTSLCTSBCTSKCTSS | |
| SCHEMBL7326904 | 0.84 | CTSL (0.57) | CTSLCTSBCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |