Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL7325314 | 0.76 | HTR2A (0.47) | SLC2A1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7317493 | 0.70 | SLC2A1 (0.52) | SLC2A1SIGMAR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7320887 | 0.68 | MEN1 (0.65) | KMT2AMEN1MTNR1BMTNR1APLAAT3 | |
| SCHEMBL9825369 | 0.68 | KCNH2 (0.50) | SLC2A1SIGMAR1POLBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7320769 | 0.67 | KCNH2 (0.49) | SLC2A1SIGMAR1POLBSMN1; SMN2KMT2A | |
| SCHEMBL7315795 | 0.67 | MEN1 (0.50) | SLC2A1SIGMAR1SMN1; SMN2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7315814 | 0.66 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL9825118 | 0.65 | SLC2A1 (0.43) | SLC2A1SIGMAR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7323256 | 0.65 | HTR2A (0.47) | KMT2AMEN1 | |
| SCHEMBL4019777 | 0.64 | SIGMAR1 (0.84) | SLC2A1SIGMAR1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661635-A | ANTIARRHYTHMIA AGENTS | MCNEILAB, INC. (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0146271-A2 | Aralykyl (arylethynyl) aralkyl amines for use as vasodilators and antihypertensives | McNeilab, Inc. (US) | 1985-06-26 | — | — | EP | disclosed |