Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7326586 | 0.99 | MAPK1 (0.53) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7326410 | 0.98 | MAPK1 (0.52) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| SCHEMBL9368351 | 0.84 | MEN1 (0.46) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9368335 | 0.83 | MAPT (0.45) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7328430 | 0.83 | MEN1 (0.47) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| SCHEMBL7325971 | 0.81 | KDM4E (0.60) | HRH3ALDH1A1SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL7324710 | 0.80 | HRH3 (0.51) | MAPK1CYP1A2TDP1HRH3KCNH2 | |
| SCHEMBL7328727 | 0.80 | FAAH (0.51) | MAPK1CYP1A2MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL5881222 | 0.80 | KDM4E (0.59) | MAPK1HRH3ALDH1A1SIGMAR1USP2 | |
| SCHEMBL22221556 | 0.79 | MAOB (0.64) | MAPK1CYP1A2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | claimed |