Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9532080 | 0.99 | MAPK1 (0.52) | HRH3MAPK1LTA4HALDH1A1CYP1A2 | |
| SCHEMBL7321964 | 0.88 | HRH3 (0.64) | HRH3SIGMAR1 | |
| SCHEMBL7317615 | 0.88 | ALDH1A1 (0.59) | HRH3MAPK1LTA4HALDH1A1CYP1A2 | |
| SCHEMBL7322566 | 0.88 | TMEM97 (0.61) | HRH3KCNH2SIGMAR1 | |
| SCHEMBL7317633 | 0.87 | HRH3 (0.61) | HRH3KDM4EMAOB | |
| Hydrochloric Acid SCHEMBL9528327 | 0.87 | USP2 (0.58) | HRH3MAPK1ALDH1A1HTR2AUSP2 | |
| Hydrochloric Acid SCHEMBL27431543 | 0.87 | SIGMAR1 (0.64) | HRH3SIGMAR1 | |
| SCHEMBL7324659 | 0.87 | MEN1 (0.59) | HRH3LTA4HALDH1A1HTR2AUSP2 | |
| Hydrochloric Acid SCHEMBL7320603 | 0.87 | TMEM97 (0.60) | HRH3KCNH2SIGMAR1 | |
| SCHEMBL7328846 | 0.86 | HRH3 (0.61) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002502-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |