SCHEMBL732541

SCHEMBL732541

CCCCCCCCCc1c(CCCCCCCC)c(-c2ccc(C)cc2)c2c(c1-c1ccc(-c3ccc(N(c4ccccc4)c4ccc(C)cc4)cc3)cc1)-c1cccc3cccc-2c13

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GCGR P47871 7/20 0.37
DHFR P00374 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
LIPE Q05469 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
MCL1 Q07820 1/20 0.32
KCNH2 Q12809 1/20 0.32
DPP4 P27487 1/20 0.32
CNR1 P21554 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2138799 0.85 GCGR (0.47) GCGRDHFRKDM4EALDH1A1KCNH2
SCHEMBL2784607 0.80 DCTPP1 (0.43) GCGRDHFRKDM4EALDH1A1TDP1
SCHEMBL728847 0.79 KCNH2 (0.37) GCGRDHFRKCNH2CNR1TDP1
SCHEMBL13510693 0.78 ENPP1 (0.41) KDM4EALDH1A1LMNA
SCHEMBL25972605 0.77 ALDH1A1 (0.41) LTB4R2KDM4EALDH1A1MCL1TDP1
SCHEMBL25974619 0.76 ALDH1A1 (0.41) LTB4R2KDM4EALDH1A1LMNAPOLB
SCHEMBL24945347 0.75 ALDH1A1 (0.40) LTB4R2KDM4EALDH1A1LMNAPOLB
SCHEMBL13510696 0.75 ALDH1A1 (0.38) KDM4EALDH1A1LMNAPOLBMCL1
SCHEMBL15681411 0.75 HSD11B1 (0.54) ALDH1A1KCNH2HSD11B1
SCHEMBL24945348 0.73 ALDH1A1 (0.41) LTB4R2KDM4EALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137822-B2 Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US disclosed
US-20110180758-A1 Light-emitting Material and Device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-07-28 US disclosed
US-20080213623-A1 7,10-bis(acryloyl, styryl, or glycidyl-substituted phenyl)fluoranthene polymerized in the presence of a nickel or palladium catalyst; photopolymerized after applied to film substrate for organic light-emitting diodes; improved stability, high efficiency and quantum yield, emission maximum in blue region BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110180758-A1 Light-emitting Material and Device OCIAD1, OCIAD2, DRD1 GCGR 3679/4885DHFR 811/4885LTB4R2 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.